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吸烟者伴有心肌梗塞与猝死发病率增加,65岁以下冠心病患者,其心肌梗塞及死亡率停止吸烟后有降低。吸烟增加冠心病之心肌梗塞及猝死机制不清楚,Levine提示血小板聚集(以下缩写PA),可能是吸烟产生动脉血栓性疾病的链节,支持这一假说的证据有:吸烟伴有血小板存活时间缩短;促进ADP诱导的PA;血小板
Smoker with increased incidence of myocardial infarction and sudden death, coronary heart disease patients under the age of 65, their myocardial infarction and mortality decreased after smoking. Smoking increases the risk of myocardial infarction and sudden death in patients with coronary heart disease. Levine suggests that platelet aggregation (abbreviated as PA) may be a link in smoking to produce arterial thrombotic disease. Evidence supporting this hypothesis is that cigarette smoking with shortened survival time of platelets ; Promote ADP-induced PA; platelets