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肝素效价测定方法系根据其抗凝血作用而建立的,所用的血源有牛、羊、兔、猪等动物的血或血浆。例如美国药典应用枸橼酸钠羊血浆;中国药典1985年版拟采用新鲜兔血、枸橼酸钠兔血浆或猪血浆。按理说,用新鲜血测定肝素效价比用贮存血浆测定的结报更切合体内的情况。不过制备的血浆分装后低温冰冻保存可随时取用而且操作方便、误差也较小是其优
Heparin potency determination method is based on the role of anti-coagulation established, the use of blood are cattle, sheep, rabbits, pigs and other animals blood or plasma. For example, the United States Pharmacopoeia application of sodium citrate sheep plasma; Chinese Pharmacopoeia 1985 edition intends to use fresh rabbit blood, sodium citrate rabbit plasma or porcine plasma. It stands to reason that the determination of heparin titer with fresh blood is more appropriate for the in vivo situation than the report of stored plasma. However, the preparation of the plasma after cryogenic cryogenic preservation can be readily available and easy to operate, the error is small is its excellent