论文部分内容阅读
目的:研究石蜡包埋癌组织制备的自体瘤苗(PETV)预防膀胱癌术后复发的近期效果。方法:PETV1.0ml多点皮内注射,每周1次,4次为一疗程。每疗程前后测定CD3+、CD4+、CD8+、CD4+/CD8+、LTT、NK和IgA、IgG、IgM。结果:16例患者治疗后CD3+、CD4+、CD4+/CD8+、LTT、NK和IgG比治疗前明显增高(P<0.05)。随访12~20个月,未见肿瘤复发。结论:PETV抗原容易获得,用以预防膀胱癌术后复发近期效果满意
Objective: To study the short-term effects of autologous tumor vaccine (PETV) prepared from paraffin-embedded cancer tissue in preventing postoperative recurrence of bladder cancer. Methods: PETV1.0ml multi-point intradermal injection, once a week, 4 times for a course of treatment. CD3+, CD4+, CD8+, CD4+/CD8+, LTT, NK and IgA, IgG, IgM were measured before and after each course of treatment. Results: After treatment, CD3+, CD4+, CD4+/CD8+, LTT, NK and IgG were significantly higher in the 16 patients than before treatment (P<0.05). Followed up for 12 to 20 months, no tumor recurrence. Conclusion: PETV antigen is easy to obtain, and its short-term effect on prevention of postoperative recurrence of bladder cancer is satisfactory