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市场上供应的扑热息痛及其复方制剂有片剂、泡腾片剂、散剂、胶囊剂、栓剂、注射剂等及各种复方制剂不下二十多种,已成为临床广泛应用的解热镇痛药。扑热复痛可引起肝功能障碍,肾功能衰竭及心脏功能异常,其中以肝功能障碍致死者最多见,国外曾有报导服巨量企图自杀者,死亡率很高。故必须引起我们的警惕。治疗量的扑热息痛是安全的,它毒性低,过敏反应罕见,不会引起高铁血红蛋白血症和溶血作用,对胃没有刺激,口服迅速吸收,与非那西丁相比,其血中浓度高峰达到较快。但急性超剂量或治疗剂量长期使用后,肝功能不良病患者,仍会出现严重毒副作用,尤其须注意没有表明含有扑热息痛药品而内含扑热
Paracetamol and its compound preparations on the market are tablets, effervescent tablets, powders, capsules, suppositories, injections and so on and more than 20 kinds of various compound preparations, has become widely used in clinical antipyretic analgesics. Paracetamol can cause liver dysfunction, renal failure and cardiac dysfunction, of which the most common cause of death caused by liver dysfunction, there have been reports of large suicide attempts in foreign countries, the mortality rate is high. It must arouse our vigilance. Treatment of paracetamol is safe, it is low toxicity, allergic reactions rare, does not cause methemoglobinemia and hemolysis, no stimulation of the stomach, oral absorption quickly, compared with phenacetin, the blood concentration peak reached Faster. However, acute overdose or therapeutic dose of long-term use, patients with liver dysfunction, there will be serious side effects, in particular, should pay attention to contain no paracetamol drugs and contain the heat