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目的讨论神经母细胞瘤诊断、治疗与预后的特点。方法分析1987年至1997年10年间收治神经母细胞瘤86例.以B超、磁共振及骨穿检查确诊。术前化疗12-18天,全部病例肿瘤切除。结果86例神经母细胞癌术后15个月内先后复发来院再次治疗48例,仅2例再次手术切除肿瘤,病理检查已趋向神经节细胞瘤。结论神经母细胞瘤已经确定诊断者首次化疗效果明显,其后是手术的良好时机。骨容和3-甲氧基-4-羟基杏仁酸检查是诊断神经母细胞瘤的较好方法。
Objective To discuss the diagnosis, treatment and prognosis of neuroblastoma. Methods 86 cases of neuroblastoma were treated during the 10 years from 1987 to 1997. B-ultrasound, magnetic resonance, and bone puncture were used to confirm the diagnosis. Preoperative chemotherapy 12-18 days, all cases tumor resection. Results Forty-eight patients with neuroblastoma relapsed within 15 months after operation and 48 patients were treated again. Only 2 patients underwent reoperation to remove the tumor. The pathological examination has been towards ganglion cell tumors. Conclusion The neuroblastoma has been confirmed to have a significant effect on the first chemotherapy of the diagnosis, followed by a good opportunity for surgery. Bone mass and 3-methoxy-4-hydroxymandelic acid examination is a better method for diagnosing neuroblastoma.