Contribution of Decreased Expression of Ku70 to Enhanced Radiosensitivity by Sodium Butyrate in Glio

• 作 者: 李宇辉 周红霞 邢恩明 任精华 董晓荣 刘红利 杨坤禹 伍钢
• 机 构: Cancer-Center,DepartmentofOncology,DepartmentofOncology
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2011年3期
• 关键词: 放射敏感性 细胞株 丁酸钠 母细胞 Western印迹 细胞存活率 胶质 U251细胞 sodium butyrate radiosensitivity K
• 基金项目: supported by a grant from National Natural Sciences Foundation of China（No.30870739）

The present study investigated the enhanced radiosensitivity of U-251 cells induced by sodium butyrate(NaB) and its possible mechanisms.Increased radiosensitivity of U251 cells was examined by clonogenic cell survival assays.The expression of Ku70 mRNA an