论文部分内容阅读
子宫颈癌是女性最常见的恶性肿瘤之一,发病率逐年上升且呈年轻化趋势。全球每年新发病例达到50万以上,死亡人数过半。相对于传统的化疗而言,肿瘤的靶向治疗是针对肿瘤细胞中特殊的分子进行的治疗,能特异性地与致癌位点相结合发生作用,具有专一性高、疗效好和毒副作用小等明显优越性,因此也将成为未来子宫颈癌治疗的主要趋势。本文总结了近年来国内外子宫颈癌分子靶向治疗研究的现状及其作用机制,旨在为开发更好的抗肿瘤治疗方法和肿瘤靶向治疗的临床应用提供理论依据。
Cervical cancer is one of the most common malignant tumors in women. The incidence rate is increasing year by year and showing a trend of younger age. The number of new cases in the world reaches more than 500,000 each year and the death toll is more than half. Compared with traditional chemotherapy, the targeted therapy of tumor is a treatment for specific molecules in tumor cells, which can specifically interact with carcinogenic sites and has the advantages of high specificity, good curative effect and small toxic and side effect And other obvious advantages, it will also become the main trend of future cervical cancer treatment. This paper summarizes the current status and the mechanism of molecular targeted therapy of cervical cancer both at home and abroad in recent years and aims to provide a theoretical basis for developing better antitumor therapy and clinical application of targeted therapy of cancer.