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对４６例肺癌组织进行光镜及电镜的对比观察，结果发现电镜下腺鳞癌的发生率远远高于光镜。光镜下诊断腺鳞癌仅１例（２．２％），而电镜诊断１２例（２６．１％）。光镜下无１例非小细胞型神经内分泌癌，电镜下２例小细胞癌、１例腺癌和２例大细胞癌胞浆中发现神经内分泌颗粒。表明在此２型肺癌的诊断中电镜观察起着很重要的作用。结果证明肺癌细胞有很高的异质性，表现为同一肿瘤中出现腺癌和鳞癌结构以及腺癌和（或）鳞癌与神经内分泌结构。同一肿瘤中出现不同组织类型的成份，支持肺癌细胞起源于支气管粘膜中干细胞的学说。
The light microscopy and electron microscopy of 46 cases of lung cancer were compared. The results showed that the incidence of adenosquamous carcinoma under electron microscope was much higher than that of light microscopy. Only one case (2.2%) of adenosquamous carcinoma was diagnosed by light microscopy, and 12 cases (26.1%) were diagnosed by electron microscopy. Under light microscopy, there was no case of non-small cell neuroendocrine carcinoma. Two cases of small cell carcinoma, one case of adenocarcinoma, and two cases of large cell carcinoma cytoplasm were found under electron microscope. It shows that the electron microscope observation plays an important role in the diagnosis of type 2 lung cancer. The results demonstrated that lung cancer cells are highly heterogeneous, manifesting as adenocarcinoma and squamous cell carcinoma structures, as well as adenocarcinoma and/or squamous cell carcinoma and neuroendocrine structures in the same tumor. Different tissue types appear in the same tumor, supporting the theory that lung cancer cells originate from stem cells in bronchial mucosa.