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５２例低温体外循环心内直视术后进行ＩＣＵ监护的患者必须行持续人工通气，全部病例选用肌松剂ＡＴＣ应用，未用或少用镇静药，效果满意。５２例均于进入ＩＣＵ立即起用ＡＴＣ微泵滴注，用量为３ｕｓ－６ｕｇ／ｋｇ／ｍｉｎ，总使用时间５～４８小时，循环稳定，停用ＡＴＣ６０～９０分钟即可拔除气管导管，全部病例无呼吸抑制并发症，未用拮抗药。本组用ＡＴＣ后，清醒时能睁眼，意识清楚，合作，循环指标稳定，机械通气正常，四肢肌松，四串电刺激器在Ｔ３／Ｔ１０．７以下，未用镇静剂３０例，于晚间用少量镇静药入睡２２例。本组进入ＩＣＵ危重患者应用ＡＴＣ有如下优点：（１）清醒合作，不燥动，减少全身氧耗。（２）保持机械通气稳定，氧供正常，有利心脏功能恢复。（３）ＡＴＣ具有作用时间短，对心肌及循环无影响；不依赖肝肾排泄，故对肝肾无毒性，且无蓄积作用和残留肌松作用。（４）持续用药减少间断用镇静药的患者燥动对抗呼吸机等不良影响。本组实践证明，在严格监护ＩＣＵ危重患者应用ＡＴＣ对重要器官无不良反应，停药短时内恢复肌力，顺利脱机。
52 patients undergoing cardiopulmonary bypass open heart surgery after ICU custody patients must be sustained artificial ventilation, all patients use muscle relaxant ATC application, no or less sedation, the effect is satisfactory. 52 cases were immediately into the ICU ATC micro-pump drip, the amount of 3us-6ug / kg / min, the total use of time 5 to 48 hours, stable circulation, disable the ATC 60 to 90 minutes to remove the tracheal tube, all cases without Respiratory depression complications, unused antagonists. This group with ATC, awake when you can open your eyes, awareness, cooperation, stable circulation indicators, normal mechanical ventilation, limbs and muscles, four string electrical stimulator below T3 / T10.7, without sedation in 30 cases, at night With a small amount of sedatives to sleep in 22 cases. The group into ICU critically ill patients with ATC has the following advantages: (1) awake cooperation, not dry move, reduce body oxygen consumption. (2) to maintain stable mechanical ventilation, oxygen for normal, favorable heart function recovery. (3) ATC has a short duration of action, no effect on myocardium and circulation; does not depend on liver and kidney excretion, it is non-toxic to the liver and kidney, and no accumulation and residual muscle relaxant effect. (4) continuous medication to reduce intermittent use of sedatives in patients with dryness against breathing machines and other adverse effects. The practice of this group has proved that in the intensive care ICU critically ill patients with ATC no significant adverse reactions to vital organs, withdrawal of muscle strength within a short time recovery, smooth offline.