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采用放射性免疫法，对脑血管病急性期与恢复期血浆内皮素浓度进行观察，并与健康同龄人对照。结果显示脑出血与梗死的急性期血浆内皮素明显升高（Ｐ＜００１）。２０天后渐恢复正常。内皮素浓度与出血部位、量及梗死的大小和多少有关，与年龄、性别无关。认为脑梗死患者及早应用钙通道阻滞有益，并可根据内皮素的浓度判断疾病的恢复及预后。
Radioimmunoassay was used to observe plasma endothelin concentration in acute and convalescent cerebrovascular disease and to compare with healthy peers. The results showed that cerebral hemorrhage and infarction acute plasma endothelin was significantly increased (P <0 01). 20 days gradually returned to normal. Endothelin concentration and bleeding sites, the amount and size and amount of infarction related, regardless of age and gender. That early application of calcium channel block in patients with cerebral infarction beneficial, and according to the concentration of endothelin to determine the recovery and prognosis of the disease.