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目的:探讨提高治疗急性重度有机磷农药中毒治愈率的方法。方法:将符合教科书诊断标准且没有合并急性心梗或脑卒中的106例急性重度有机磷农药中毒患者分为2组,即治疗组(2011年5月至今)和对照组(2011年5月以前)。治疗组在对照组常规治疗的基础上第一时间给予可拉明针1~2支(0.375g/支)静脉推注。结果:治疗组在全血胆碱酯酶活力恢复时间、死亡与反跳例数等观察指标方面均优于对照组。结论:在常规治疗急性重度有机磷农药中毒的基础上第一时间给予呼吸兴奋剂可拉明,可加快患者康复,降低死亡率,提高治愈率。
Objective: To explore ways to improve the cure rate of acute severe organophosphorus pesticide poisoning. Methods: One hundred and sixty patients with acute severe organophosphorus pesticide poisoning who did not have acute myocardial infarction or stroke complicated with textbook diagnostic criteria were divided into two groups: treatment group (May 2011 to present) and control group (before May 2011) ). The treatment group was given intravenous injection of 1 ~ 2 (0.375g / branch) of kolaamine for the first time on the basis of routine treatment in the control group. Results: The treatment group in the whole blood cholinesterase activity recovery time, death and rebound count and other indicators were better than the control group. CONCLUSION: Clarithromycin, a respiratory stimulant, can be accelerated for the first time on the basis of conventional treatment of acute severe organophosphorus pesticide poisoning. It can speed up patient rehabilitation, reduce mortality and increase cure rate.