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目的评估应用经鼻面罩正压通气治疗对阻塞性睡眠呼吸暂停(OSA)患者心律失常的治疗效果。方法选取我院2014年5月~2016年5月收治的OSA停合并心律失常患者80例,依据随机数字表法将这些患者分为药物治疗联合经鼻面罩正压通气治疗组(联合治疗组,n=40)和单纯药物治疗组(单独治疗组,n=40)两组,对两组患者的HR、AHI、最低SaO_2、(中文名?)TSTSaO_2<90%及夜间心律失常发生次数、临床疗效、临床症状消失时间及住院时间进行统计分析。结果联合治疗组患者的夜间最慢HR、SaO_2low均显著高于单独治疗组(P<0.05),夜间最快HR、AHI、TSTSaO_2<90%均显著低于单独治疗组(P<0.05),夜间心律失常发生次数显著少于单独治疗(P<0.05),治疗的总有效率92.5%(37/40)显著高于单独治疗组72.5%(29/40,P<0.05),临床症状消失时间及住院时间均显著短于单独治疗组(P<0.05)。结论经鼻面罩正压通气治疗阻塞性睡眠呼吸暂停患者心律失常的治疗效果良好。
Objective To evaluate the therapeutic effect of nasal mask positive pressure ventilation on arrhythmia in obstructive sleep apnea (OSA) patients. Methods Eighty patients with OSA discontinuation and arrhythmia admitted from May 2014 to May 2016 in our hospital were divided into three groups according to the random number table: drug treatment combined with nasal mask positive pressure ventilation group (combination therapy group, (n = 40) and simple drug treatment group (n = 40). The HR, AHI, lowest SaO_2, TSTSaO_2 <90% and the incidence of nocturnal arrhythmia in both groups were compared between two groups Efficacy, disappearance of clinical symptoms and hospital stay for statistical analysis. Results The lowest nighttime HR and SaO_2low in the combined treatment group were significantly higher than those in the untreated group (P <0.05), the fastest nighttime HR, AHI and TSTSaO_2 <90% were significantly lower than those in the untreated group (P <0.05) The total effective rate of treatment was 92.5% (37/40), which was significantly higher than that of the untreated group (72.5%, 29/40, P <0.05), the disappearance of clinical symptoms and The length of hospital stay was significantly shorter than that of the untreated group (P <0.05). Conclusion Nasal mask positive pressure ventilation in patients with obstructive sleep apnea arrhythmia treatment effect is good.