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经典梅尼埃病模型是通过破坏内淋巴囊而获得的，膜迷路积水是渐进的过程，听力变化缺少波动性，因此，是非生理意义性模型。作者创立分两期法形成内淋巴积水的豚鼠模型。健康自化雌性豚鼠，经颅后窝入路切除内淋巴囊，术后第三周起予腹膜内注射肾上腺皮质醇（Aldostrone）100微
The classical Meniere’s disease model is obtained by destroying the endolymphatic sac. The labyrinth of the labyrinth is a gradual process and the lack of variability in hearing changes is therefore a non-physiological significance model. The authors created a guinea pig model of endolymphatic hydrops in two stages. Healthy spontaneous female guinea pigs, resection of the endolymphatic sac through the posterior fossa posterior approach, after the first three weeks after intraperitoneal injection of adrenocortical alcohol (Aldostrone) 100 micro