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[目的]探讨可必特雾化吸入方式治疗慢性阻塞性肺疾病（COPD）急性加重期的疗效及其对肺功能的影响。[方法]2011年5月至2013年4月在本院确诊为COPD急性加重期75例患者作为研究对象。以数字法随机分为对照组（39例）和观察组（36例）。对照组患者行常规治疗处理。观察组患者在对照组治疗基础上实施可必特雾化吸入。观察对比两组治疗结果和肺功能水平变化。[结果]通过治疗后，两组患者动脉氧分压（PaO2），二氧化碳分压（PaCO2）及pH值均较治疗前有所改善，且差异有显著性（均 P＜0．05），与对照组相比，观察组改善更为明显，且差异均有显著性（均 P ＜0．05）。观察组疗效为优者占69．44％（25/36），优良率为94．44（34/36），均显著高于对照组的35．90％（14/39），74．36％（29/39），且两组相比较差异均有显著性（均 P ＜0．05）。[结论]可必特雾化吸入法治疗COPD急性加重期能够有效缓解病情且明显改善患者肺功能。“,”[Objective] To explore the efficacy of Combivent inhalation for the treatment of acute exacerba-tion of chronic obstructive pulmonary disease(COPD) and its effect on pulmonary function .[Methods]A total of 75 patients diagnosed as acute exacerbation of COPD in our hospital from May 2011 to April 2013 were en-rolled in the study and randomly divided into control group( n=39) and observation group( n=36) .The con-trol group received routine treatment ,while the observation group additionally received Combivent inhalation based on the treatment of control group .The treatment results of two groups were compared and lung function changes of each group were observed .[Results]Compared with before treatment ,PaCO2 ,PaO2 ,and pH val-ue of two groups after treatment were improved ,and there was significant difference between two groups (all P<0 .05) .Compared with control group ,the improvement of observation group was more obvious ,and there was significant difference between two groups(all P<0 .05) .The observation group with excellent efficacy ac-counted for 69 .44% (25/36) .The excellent and good rate of observation group was 94 .44% (34/36) which was markedly higher than that of control group[35 .90% (14/39) and 74 .36% (29/36)] ,and there was signifi-cant difference between two groups(all P <0 .05) .[Conclusion]Combivent inhalation for the treatment of a-cute exacerbation of COPD can effectively alleviate the condition and improve lung function of patients .