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目的：观察正常孕妇１８３例、妊高征１２８例不同孕期的血清Ｃａ、ＢＧＰ水平及补充钙剂治疗后的变化。方法：正常孕妇及妊高征孕妇服钙剂治疗，另选未用药者作对照组，分别取静脉血３ｍｌ，自然凝固后２５００ｒ／ｍｉｎ离心２０ｍｉｎ，测血清ＢＧＰ、血清Ｃａ。结果：妊娠期血清Ｃａ、ＢＧＰ均低于正常，随妊娠进展降至最低点；妊高征患者血Ｃａ、ＢＧＰ又低于正常孕妇；妊高征程度越重，血Ｃａ下降越明显。结论：服用钙剂治疗后，血清Ｃａ、ＢＧＰ较用药前显上升，提示血Ｃａ下降与血压升高及先兆子痫发生有明显关系，补充钙剂不但可以降低妊高征的发生率，还可减轻妊高征的危险性。
Objective: To observe the changes of serum Ca and BGP levels in 183 pregnant women and 128 pregnant women with PIH during different stages of pregnancy and the effect of calcium supplementation. Methods: Normal pregnant women and pregnant women with pregnancy-induced hypertension received calcium treatment, while those who had not used drugs as control group were given 3 ml of venous blood respectively. After centrifugation at 2500 r / min for 20 minutes, the serum BGP and serum Ca were measured. Results: Serum levels of Ca and BGP during pregnancy were both lower than normal and decreased with the progress of pregnancy. Blood Ca and BGP in patients with PIH were lower than those in normal pregnant women. The more serious PIH was, the more obvious the decline of blood Ca was. Conclusion: After taking calcium treatment, serum Ca and BGP increased significantly compared with those before treatment, suggesting that there is a clear relationship between the drop of blood Ca and the rise of blood pressure and preeclampsia. Calcium supplement not only can reduce the incidence of PIH, but also Reduce the risk of pregnancy-induced hypertension.