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芫花萜是从芫花根中提出的结晶,用它制成纯酒精制剂已于1976年开始临床应用,经羊膜腔内外注药,进行中期妊娠引产,具有效果良好、副反应小、安全、药源广、制备简便、价格低等优点,1977年由上海市通过鉴定,并逐步推广应用。为了提高药物的安全性,自1978年6月起临床上改用50％酒精制剂。现将二种制剂的临床效果及药物副作用比较如下: 临床资料一、对象、用药剂量及注药途径:二组对象皆为妊娠3.5～6个月健康孕妇,需终止妊娠者。妊娠4～6个月者,采用羊膜腔内注药,剂量0.07 mg。妊娠3.5～4个月者,采用羊膜腔外注药,剂量0.08 mg。在注药前皆需用注射用水稀释到8 ml。
Yuntan ternary is from the roots of Daphne genkwa proposed crystallization, made of pure alcohol preparation with it has been in clinical application since 1976, the injection of amnion inside and outside the mid-term pregnancy induction of labor, with good results, side effects of small, safe, Wide source of medicine, preparation of simple, low price, in 1977 by the Shanghai municipal identification, and gradually promote the application. In order to improve the safety of drugs, as of June 1978 since the clinical use of 50% alcohol preparation. Now the clinical effects of two preparations and drug side effects are as follows: Clinical data First, the object, dosage and injection route: two groups of patients are pregnant 3.5 to 6 months healthy pregnant women, need to terminate the pregnancy. 4 to 6 months of pregnancy, the use of amniotic injection, a dose of 0.07 mg. 3.5 to 4 months of pregnancy, the use of amniotic fluid injection, a dose of 0.08 mg. Dilute to 8 ml with water for injection before filling.