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本文通过透射电子显微镜观察感染日本血吸虫病的小白鼠经硝硫氰胺治疗后,其体内虫体体壁的超微结构的变化。结果表明,硝硫氰胺对血吸虫虫体壁包括表皮,肌层和皮层细胞的超微结构都有程度不等的影响。并且发现表皮内的二种主要包含物,多膜层小泡(M、L、V、)及盘状颗粒(D、G)的减少与消失对表皮的超微病理改变有密切的关系。同时,对血吸虫虫体标本超薄切片的制备方法也进行了探索。
In this paper, transmission electron microscopy was used to observe the changes of the ultrastructure of the body wall of mice infected with nitramine after schistosomiasis-infected mice. The results showed that the nitrite and thiamine on the body wall, including the epidermis, muscle and cortical ultrastructure have varying degrees of influence. It was also found that the reduction and disappearance of two major inclusions in the epidermis, multilamellar vesicles (M, L, V) and discoid particles (D, G) were closely related to the ultrastructural changes of epidermis. At the same time, the preparation method of schistosome parasitic specimen ultrathin sections was also explored.