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目的：探讨肿瘤高发区居民食管癌胃癌发病的相关因素及其特征。方法：对食管癌胃癌高发区３０岁以上自然人群１２３０人进行了五年前瞻性研究，按进入研究时的年龄暴露水平，用Ｍ－Ｈ法计算单一因素及多个因素的比值比，对相对危险进行估价。结果：发现上消化道病史（ＯＲ＝２．８４）、症状（ＯＲ＝４．６３），吸烟（ＯＲ＝３．４０）等因素与发病密切相关；而多吃豆类和／或豆制品（ＯＲ＝０．２３）以及蛋类（ＯＲ＝０．７９）等具有明显的保护作用。并发现这些因素之间的相互影响。结论：对生活在肿瘤高发区的４０岁以上成年人，特别是有上消化道病史和（或）症状，有癌症家族史且又吸烟者，应加强医学监测并采取积极的预防措施
Objective: To explore the related factors and characteristics of gastric cancer in esophageal cancer in residents with high incidence of tumor. METHODS: A prospective 5-year prospective study was performed on 1230 people over 30 years of age in high-risk areas of esophageal cancer. The age-exposure levels at entry into the study were used to calculate the odds ratios of single factors and multiple factors using the M-H method. Risk assessment. Results: It was found that the history of upper digestive tract (OR=2.84), symptoms (OR=4.63), smoking (OR=3.40) and other factors were closely related to morbidity; while eating more beans and/or soy products ( OR=0.23) and eggs (OR=0.79) have obvious protective effects. And discover the mutual influence between these factors. Conclusions: For adults over the age of 40 living in high-incidence areas of the tumor, especially those with history and/or symptoms of upper gastrointestinal diseases, family history of cancer, and smokers, medical surveillance should be strengthened and positive preventive measures should be taken.