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目的:探讨声辐射力脉冲成像(Acoustic radiation force impulse,ARFI)技术定量诊断弥漫性脂肪肝的临床应用价值。方法:应用ARFI技术对59例弥漫性脂肪肝患者和健康对照30例进行肝脏弹性定量检测,比较并分析各组差异。结果:各组间肝脏ARFI测值存在显著差异(P<0.01),重度脂肪肝组与其他3组间ARFI测值的差异均存在统计学意义(P<0.01);ARFI测值与脂肪肝程度存在正相关(r=0.372,P<0.05),随着脂肪肝程度加重,肝脏ARFI测值逐渐增高。结论:ARFI技术做为无创性检测肝脏弹性的方法,有助于量化评价弥漫性脂肪肝病变程度。
Objective: To investigate the clinical value of Acoustic radiation force impulse imaging (ARFI) in quantitative diagnosis of diffuse fatty liver disease. Methods: Fifty-nine patients with diffuse fatty liver and 30 healthy controls were enrolled in this study. The elasticity of liver was measured by ARFI technique. The differences among groups were compared and analyzed. Results: There was significant difference in ARFI between the two groups (P <0.01). There was significant difference in ARFI between the severe fatty liver group and the other three groups (P <0.01) (R = 0.372, P <0.05). As the degree of fatty liver increased, the ARFI value of liver increased gradually. Conclusion: The ARFI technique is a noninvasive method to detect liver elasticity and is helpful to quantitatively evaluate the degree of diffuse fatty liver disease.