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AIM:To explore the prevalence of gallstone disease(GSD)in Taiwan and condition-associated factors relatedto it.METHODS:We studied a total of 2386 healthy adults(1235 males and 1151 females)voluntarily admittedto Cheng Hsin General Hospital for a paid physicalcheck-up between January 2002 and December 2002.Blood samples and ultrasound sonography results werecollected.RESULTS:The overall prevalence of GSD among thisstudy-population was 5.3%,including 1.7%(n=40)having a single stone,2.3%(n=55)having multiplestones,and 1.3%(n=31)having cholecystectomy.The prevalence revealed a statistically significantincrease with increasing age(P<0.0001).Femalesexhibited a greater prevalence of multiple stones thandid males(3.0% vs 1.7%,P=0.04).Using multiplelogistic regression analysis,the following appeared tobe significantly related to the prevalence of GSD:olderage(40-49 years vs<40 years,OR=1.63[95% CI:0.76-3.48],50-59 years vs<40 years,OR=4.93[95% CI:2.43-9.99],60-69 years vs<40 years,OR=6.82[95%CI:3.19-14.60],≥70 years vs<40 years,OR=10.65[95% CI:4.78-23.73]),higher BMI(≥27 kg/m~2 vs<24kg/m~2,adjusted OR=1.74[95% CI:1.04-2.88]),andhigher FPG(≥126 mg/dL vs<110 mg/dL,OR=1.71,95%CI:1.01-2.96).CONCLUSION:Older age(≥50 years),obesity(BMI≥27 kg/m~2),and type 2 diabetes(FPG≥126 mg/dL)areassociated with the prevalence of GSD.
AIM: To explore the prevalence of gallstone disease (GSD) in Taiwan and condition-associated factors related to it. METHODS: We studied a total of 2386 healthy adults (1235 males and 1151 females) voluntarily admitted to Cheng Hsin General Hospital for a paid physical check- up between January 2002 and December 2002. Blood samples and ultrasound sonography results were collected .RESULTS: The overall prevalence of GSD among this population-study was 5.3%, including 1.7% (n = 40) having a single stone, 2.3% (n = 55 ) with multiple lesions, and 1.3% (n = 31) having cholecystectomy.The prevalence revealed a significant significant increase with age (P <0.0001) .Femalesexhibited a greater prevalence of multiple stones thandid males (3.0% vs 1.7%, P = 0.04) . Using multiple logistic regression analysis, the following appeared to be significantly related to the prevalence of GSD: olderage (40-49 years vs <40 years, OR = 1.63 [95% CI: 0.76-3.48], 50-59 years vs <40 years , OR = 4.93 [95% CI: 2.43-9.99], 60-69 years vs <40 years, OR = 6.82 [95% CI : 3.19-14.60], ≥70 years vs <40 years OR = 10.65 [95% CI: 4.78-23.73]), higher BMI (≥27 kg / m 2 vs <24 kg / m 2, adjusted OR = 1.74 (95% CI: 1.04-2.88)), andhigher FPG (≥126 mg / dL vs <110 mg / dL, OR = 1.71, 95% CI: 1.01-2.96) .CONCLUSION: Older age (BMI ≥ 27 kg / m ~ 2), and type 2 diabetes (FPG ≥ 126 mg / dL) areassociated with the prevalence of GSD.