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目的探讨高非高密度脂蛋白胆固醇(non-HDL-C)血症在青少年中的检出率及相关危险因素,为探讨儿童高脂血症的有效控制方法提供基础数据。方法使用分层整群随机抽样方法,对秦皇岛地区3 136名13~17岁汉族青少年的non-HDL-C水平进行横断面调查。结果高non-HDL-C血症检出率为1.2%。三酰甘油和腰围正常组青少年高nonHDL-C血症检出率为0.5%,而HTWC组青少年检出率为9.8%。校正性别、年龄、糖尿病家族史和高血压家族史后,HTWC组青少年高non-HDL-C血症检出率是三酰甘油和腰围正常组青少年的19.696倍(95%CI=8.325~46.595,P<0.01)。结论HTWC表型与青少年高non-HDL-C血症密切相关,为青少年高non-HDL-C血症的危险因素。
Objective To investigate the prevalence and risk factors of non-HDL-C in adolescents and provide basic data for effective control of hyperlipidemia in children. Methods A stratified cluster random sampling method was used to investigate the non-HDL-C levels of 3 136 adolescents aged 13-17 in Qinhuangdao. Results The detection rate of high non-HDL-C was 1.2%. In high-triglyceride group and normal waist-high group, the detection rate of high non-HDL-C in adolescents was 0.5%, while that in HTWC group was 9.8%. After adjusting for gender, age, family history of diabetes and family history of hypertension, the detection rate of high non-HDL-C in adolescents in HTWC group was 19.696 times that of the normal group (95% CI = 8.325 ~ 46.595, P <0.01). Conclusion The HTWC phenotype is closely related to high non-HDL-C in adolescents and is a risk factor for adolescent with high non-HDL-C.