Mitofusin activation enhances mitochondrial motility and promotes neuroregeneration in CMT2A

• 作 者: Gerald W.Dorn II
• 机 构: DepartmentofInternalMedicine
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2021年11期
• 关键词: MOTILITY ACTIVATION REGENERATION
• 基金项目: supported by NIH R35HL135736,R41NS113642,R41NS115184,and Research Grant 628906 from the Muscular Dystrophy Association(to GWD).

Human brains represent only 2%of body mass,but their high relative metabolic activity accounts for~20%of total body adenosine triphosphate(ATP)consumption.ATP generated by neuronal mitochondria fuels nerve signaling and homeostatic repair.In the periphera