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设定新四兰白兔头部为一靶区，外加磁场，经兔耳缘静脉注射磁性平阳霉素微球（NPMS），观察MPMS在体内分布情况。并阐述外加磁场强度及时间对微球在靶区定位的影响。结果提示：①经外加磁场作用下的MPMS有较好的靶向分布性，且与外加磁场作用的时间、强度相平行。②海绵状血管瘤与周围的动静脉存在广泛交通，瘤腔注药后往往迅速流失，MPMS在外加磁场作用下，可将药物浓集在瘤腔，通过药物缓释作用，延长对瘤腔内膜的损伤作用，增加治疗效果。
The head of the new four-lane white rabbit was set as a target area and an external magnetic field was applied. Magnetic pingyangmycin microspheres (NPMS) were injected into rabbit ear veins to observe the distribution of MPMS in the body. The effect of the applied magnetic field intensity and time on the localization of the microspheres in the target region was also described. The results suggest that: 1 MPMS under the applied magnetic field has a better target distribution and parallels the time and intensity of the applied magnetic field. 2 Cavernous hemangiomas have extensive traffic with the surrounding arteriovenous veins. The tumor cavity often loses rapidly after injection. Under the influence of an external magnetic field, the MPMS can concentrate the drug in the tumor cavity and extend the tumor cavity through the drug’s sustained release. The damage of the membrane increases the therapeutic effect.