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肾综合征出血热（HFRS）家鼠型病毒株237，经过酶斑选育后，获得的237七毒株，与原来的毒株相比，其生物学特性发生较大的变化，表现在沙鼠肾细胞上增殖的病毒滴度由原来的106.0TCID50／ml增至107.5TCID50／ml；培养液中的抗原量由原来的RPHA1：16增至1：04，由它制成的疫苗免疫家兔的血清，对UR病毒的中和抗体滴度，由原来的≤1:10，增至1：10～≥1:40。表明Z37－5毒株适用于制造灭活疫苗。
Compared with the original strain, the 237 strains of HFRS-induced murine virus strain 237, after being blotted with the enzyme blot, had a great change in their biological characteristics, The virus titer of mouse kidney cells was increased from 106.0TCID50 / ml to 107.5TCID50 / ml. The amount of antigen in the culture medium was increased from 1: 16 to 1: 04. The vaccine made from it was used to immunize rabbits Of the serum, neutralizing antibodies against UR virus titer, from the original ≤ 1:10, to 1: 10 ~ ≥ 1:40. The Z37-5 strain is suitable for making inactivated vaccines.