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目的研究去炎松与道诺霉素脂质体联合应用对玻璃体切除兔眼视网膜的影响。方法对１６只兔双眼行玻璃体切除术并分为４组，分别在各组兔的１眼玻璃体内注入空白脂质体、１ｍｇ去炎松、１０μｇ道诺霉素脂质体，另１眼作对照。观察术后２８天内眼底和ＥＲＧｂ波的变化以及２８天时视网膜结构的变化。结果联合用药组ＥＲＧｂ波较空白脂质体组、去炎松组有升高（Ｐ＜０．０５），而与道诺霉素脂质体组无差异（Ｐ＞０．０５），光镜和电镜下视网膜结构无损害。结论１ｍｇ去炎松和１０μｇ道诺霉素脂质体联合应用对玻璃体切除兔眼视网膜无损害
Objective To study the effect of combined use of triamcinolone and daunorubicin liposome on vitreoretinal rabbit retina. Methods 16 eyes of two rabbits underwent vitrectomy and divided into 4 groups. One of the rabbits in each group was injected with liposomes, 1 mg of triamcinolone acetonide, 10 μg of daunomycin liposomes in one eye of rabbits, Control. The changes of ocular fundus and ERGb wave in 28 days after operation and the changes of retinal structure in 28 days were observed. Results Compared with the blank liposome group and the triamcinolone acetonide group, the ERGb wave in the combination group was significantly increased (P <0.05), but not significantly different from that in the daunomycin liposome group (P> 0.05) And electron microscopy retinal structure without damage. Conclusion 1mg triamcinolone and 10μg daunomycin liposome combined with no effect on vitreoretinal rabbit retina