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目的:探讨非小细胞肺癌不同肺叶切除手术方法对术后长期生活质量(QOL)影响。方法:采用生活质量测定量表核心量表(QLQ-C30)调查从2005年4月1日至2006年3月31日在我科治疗的80例非小细胞肺癌患者,将其分为两组,A组:肺叶切除(单叶/双叶切除);B组:全肺切除术。对其术前和术后3,6和12个月的QLQ-C30得分与参考值进行比较。结果:①术前术后生活质量相比较。功能方面,术后情绪功能,体力功能显着下降;症状方面,术后呼吸困难,疼痛明显加重;术后第3个月疲乏明显加重;术后第3,6个月经济困难较术前明显加重;②两组术后生活质量相比较,功能方面,术后B组体力功能、角色功能、情绪功能及总体状况显著的降低;症状方面,B组较A组,术后疲乏显著升高,第3-12个月疼痛,第3,6个月呼吸困难均显著升高。结论:术后生活质量与术前比较,全肺切除对患者生活质量影响明显。比较两种方法,全肺切除组较肺叶切除患者术后长期生活质量下降明显。
Objective: To investigate the effect of different lobectomy procedures on postoperative long-term quality of life (QOL) in non-small cell lung cancer. Methods: Eighty non-small cell lung cancer patients treated in our department from April 1, 2005 to March 31, 2006 were surveyed using the QLQ-C30 scale, and were divided into two groups , Group A: lobectomy (single / double lobectomy); Group B: pneumonectomy. The QLQ-C30 scores were compared with the reference values before and 3,6 and 12 months postoperatively. Results: ① preoperative and postoperative quality of life compared. Function, postoperative emotional function, physical function decreased significantly; symptoms, postoperative dyspnea, pain was significantly increased; 3 months after the fatigue was significantly worse; 3,6 months after the economic difficulties were significantly more preoperative Compared with group A, postoperative fatigue was significantly higher in group B than that in group B. In terms of function, postoperative B group had significantly lower body function, role function, emotional function and general condition. Pain in the 3rd to 12th month and dyspnea in the 3rd and 6th month were significantly increased. Conclusion: The postoperative quality of life compared with preoperative, pneumonectomy on the quality of life of patients significantly. Comparing the two methods, the long-term quality of life in the pneumonectomy group was significantly lower than that in the lobectomy group.