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MDS是一组由干细胞恶性变所致分化障碍,引起无效造血的克隆性综合征。Newman等所见的28例MDS患者中16例测得HbF值升高[1]。自1996年以来,我们通过抗碱法检测了HbF含量增高的MDS患者46例、临床诊断明确良性血液病患者26例,对两组HbF含量增高程度及骨髓红系增生状态进行分析、探?
MDS is a group of clonal syndromes caused by dysplastic differentiation of stem cells that cause ineffective hematopoiesis. HbF was elevated in 16 of the 28 MDS patients seen by Newman et al [1]. Since 1996, we detected 46 cases of MDS patients with elevated HbF levels by anti-alkali method, 26 patients with definite benign blood diseases in clinical diagnosis, and analyzed the level of HbF and erythroid hyperplasia status in both groups.