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环境中化学物质对人体健康的影响问题,日益引起人们的关心。从发病学的角度来看,化学物质作用于人体后所产生的不良反应可能有以下三种情况: 1.毒物引起的急性及慢性中毒性病变; 2.特殊的致畸、致突变及致癌作用; 3.作为免疫原进入机体后引起异常的免疫反应(过敏反应或免疫抑制),造成机体的组织损伤或生理功能紊乱。过去在卫生毒理学实验研究中,对化学物质的一般毒性研究注意较多。近年来,随着对化学物质毒理作用的认识日益深化,卫生毒理
The impact of chemicals in the environment on human health has drawn increasing public concern. From a epidemiological point of view, the adverse effects of chemical substances on the human body may have the following three conditions: 1. Poison-induced acute and chronic toxic lesions; 2. Special teratogenic, mutagenic and carcinogenic effects ; 3. As an immunogen into the body caused by an abnormal immune response (allergic reaction or immunosuppression), causing the body’s tissue damage or physiological dysfunction. In the past in the experimental study of toxicology of health, more attention was paid to the general toxicity of chemicals. In recent years, with the deepening understanding of toxicological effects of chemicals, health toxicology