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[目的]了解奉贤区初、高中毕业生乙型肝炎病毒(HBV)感染状况,为学生的乙肝防治工作提供科学依据。[方法]对2004~2008年上海市奉贤区初、高中毕业生体检资料中血清HBsAg、丙氨酸氨基转移酶(ALT)检测资料进行分析。[结果]2004~2008年合计检测43 301人,HBsAg阳性的935例,阳性率为2.16%,呈逐年下降趋势(P<0.01);ALT异常的71例,异常率为0.16%。其中HBsAg阳性、ALT异常的24例(高中毕业生16例,初中生8例),占检测总人数的0.06%。[结论]奉贤区初、高中毕业生HBV感染率较低。
[Objective] To understand the status of hepatitis B virus (HBV) infection among students in early and middle school in Fengxian District and provide scientific basis for the prevention and control of hepatitis B. [Methods] The data of serum HBsAg and alanine aminotransferase (ALT) in the physical examination data of early and high school graduates from 2004 to 2008 in Fengxian District of Shanghai were analyzed. [Results] A total of 43 301 HBsAg positive cases were detected from 2004 to 2008, with a positive rate of 2.16%. The positive rate was 2.16% (P <0.01). The abnormal ALT rate was 0.16% in 71 cases. Among them, 24 cases of HBsAg positive and ALT abnormalities (16 high school graduates and 8 junior high school students) accounted for 0.06% of the total. [Conclusion] The prevalence of HBV infection among junior and senior high school students in Fengxian district was low.