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作者研究了Na_2SeO_3对柯萨奇B_5病毒在细胞内复制的影响。通过向营养液中加入一定剂量的Na_2SeO_3培养细胞,使细胞传至3~10代,柯萨奇B_5病毒在细胞内的增殖量降低,而细胞存活率明显增高,与对照组相比,差异显著。这种抑制病毒增殖作用的原因,不是Na_2SeO_3对病毒的直接灭活作用,而可能是Na_2SeO_3使细胞内发生了某些代谢改变,达到了一定程度地抑制病毒增殖的作用。
The authors studied the effect of Na_2SeO_3 on intracellular replication of Coxsackie B_5 virus. By adding a certain dose of Na_2SeO_3 to the nutrient solution, the cells were passed to the 3rd to 10th passages. The proliferation of Coxsackie B_5 virus in the cells was reduced, and the cell survival rate was significantly increased. The difference was significant compared with the control group. . The reason for this inhibition of virus proliferation is not the direct inactivation of virus by Na 2 SeO 3 , but it may be that Na 2 SeO 3 causes some metabolic changes in the cells, which has achieved a certain degree of inhibition of virus proliferation.