Standard Versus Extended Pancreaticoduodenectomy in Treating Adenocarcinoma of the Head of the Pancr

• 作 者: Jun Gong Gang Mai Zhen-jiang Zheng Guang-ming Xiang Wei-ming Hu Bo-le Tian Zhao-da Zhang Xu-bao Liu
• 机 构: Department of Hepatobiliary and Pancreatic Surgery,Sichuan Academy of Medical Science and Sichuan Pr
• 出 处: Chinese Medical Sciences Journal
• 发表日期: 2013年02期
• 关键词: pancreas cancer pancreaticoduodenectomy standard resection extended resection

Objectives To compare the postoperative complications and survival of standard pancreatoduodenectomy (SPD) and extended pancreatoduodenectomy (EPD) in patients with resectable adenocarcinoma of the head of the pancreas.Methods Between January 1994 and December 2011,165 patients with biopsy-proven adenocarcinoma of the pancreatic head were treated in West China Hospital,among whom 93 underwent SPD and 72 had EPD.Complications and survival after the surgery were analyzed retrospectively.Results The median operation time of the EPD group was longer compared with the SPD group (375 minutes vs.310 minutes,P<0.01),the volume of blood transfusion was larger (700 mL vs.400 mL,P<0.05),while the median hospital stay (13.5 days vs.12 days,P = 0.79) and the total complication rates were comparable (34.7% vs.32.4%,P=0.93).The total recurrence rates of the SPD and EPD groups were not significantly different (52.7% vs.43.1%,P=0.83).No significant differences were found between the SPD and EPD groups in 1-year (81.7% vs.86.1%),3-year (38.7% vs.43.1%),5-year (16.7% vs.19.4%),and median survivals (19.8 months vs.23.2 months,P= 0.52).Conclusion The postoperative complications and survival donot differ significantly between SPD and EPD.

Objectives To compare the postoperative complications and survival of standard pancreatoduodenectomy (SPD) and extended pancreatoduodenectomy (EPD) in patients with resectable adenocarcinoma of the head of the pancreas. Methods Between January 1994 and December 2011,165 patients with biopsy-proven adenocarcinoma of the pancreatic head were treated in West China Hospital, among whom 93 underwent SPD and 72 had EPD. Applications and survival after the surgery were analyzed retrospectively. Results The median operation time of the EPD group was longer than with the SPD group (375 minutes vs. 310 while the median hospital stay (13.5 days vs. 12 days, P = 0.79) and the total complication rates were (34.7% vs.32.4%, P = 0.93) .The total recurrence rates of the SPD and EPD groups were not significantly different (52.7% vs.43.1%, P = 0.83) .No significant differences were found between the SPD and EPD groups in 1-year (81.7% vs.86.1%), 3-year (38.7% vs.43.1%), 5-year (16.7% vs.19.4%), and median survivals (19.8 months vs.23.2 months, P = 0.52) .Conclusion The postoperative complications and survival donot differ significantly between SPD and EPD.