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目的探索腹腔镜子宫肌瘤剥除术中用益母草+缩宫素注射液及垂体后叶素止血的特点。方法 53例子宫肌壁间肌瘤病员,随机分为治疗组(27例),对照组(26例)。治疗组术中予益母草注射液+缩宫素注射液宫体注射;对照组术中予垂体后叶素宫体注射。观察2组:术中失血量及手术时间;平均动脉压最大波动幅值及心率最大波动幅值。结果术中失血量治疗组[(73.81±12.33)ml]与对照组[(73.22±8.70)ml]相当(P=0.085,P>0.05);手术时间治疗组[(62.18±7.68)min]与对照组[(62.62±11.30)min]相当(P=0.191,P>0.05);平均动脉血压最大波动幅值治疗组[(6.93±3.81)mm Hg]小于对照组[(26.15±9.56)mm Hg](P=0.000,P<0.05);心率最大波动幅值治疗组[(5.55±3.69)次/min]小于对照组[(13.50±8.65)次/min](P=0.000,P<0.05)。结论益母草+缩宫素注射液在腹腔镜子宫肌瘤剥除术中能提供与垂体后叶素相近的止血作用,同时具有对循环系统功能干扰更小的特点。
Objective To explore the characteristics of laparoscopic hysteromyoma stripping with Motherwort + oxytocin injection and pituitrin to stop bleeding. Methods 53 patients with uterine fibroids were randomly divided into treatment group (n = 27) and control group (n = 26). The treatment group intraoperative injection of Motherwort + oxytocin injection of uterine body injection; control group intraoperative pituitary injection of uterus. Two groups were observed: intraoperative blood loss and operation time; mean arterial pressure maximum amplitude and maximum amplitude of heart rate fluctuations. Results The blood loss in operation group was significantly higher than that in control group [(73.81 ± 12.33) ml vs (73.22 ± 8.70) ml (P = 0.085, P> 0.05) The mean maximum arterial blood pressure in the treatment group [(6.93 ± 3.81) mm Hg] was smaller than that in the control group [(26.15 ± 9.56) mm Hg [(62.62 ± 11.30) min] (5.55 ± 3.69) times / min in the treatment group [(13.50 ± 8.65) times / min] (P = 0.000, P <0.05) . Conclusion Motherwort + oxytocin injection can provide the hemostatic effect similar to vasopressin in laparoscopic hysterectomy, meanwhile, it has the characteristics of less interference with circulatory system.