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目的:了解我市药品不良反应(ADR)的发生特点及ADR/ADE报告中存在的问题,促进临床合理用药,提高ADR监测工作质量。方法:利用Excel软件对收集的ADR/ADE报告病例的性别、年龄、涉及的药品种类、ADR临床表现、报告人职业等进行分类统计。结果:由抗微生物药物和注射途径给药引起的ADR/ADE所占比例最高,损伤的器官/系统以皮肤及其附件最为常见,报告质量、数量需提高。结论:应进一步加强ADR监测和宣传工作,减少或避免ADR/ADE的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our city and the problems in ADR / ADE report, to promote clinical rational use of drugs and to improve the quality of ADR monitoring. Methods: The gender, age, types of medicines involved, the clinical manifestations of ADR, occupations of the reporters and so on were collected by using Excel software to classify the collected cases of ADR / ADE. Results: ADR / ADE caused by antimicrobial drug and injection route had the highest proportion. The damaged organ / system was the most common in the skin and its appendix, and the quality and quantity of the report should be increased. Conclusion: ADR monitoring and advocacy efforts should be further strengthened to reduce or avoid the occurrence of ADR / ADE.