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慢性肾脏病患者心血管疾病的发病率、病死率明显高于普通人群，且其出现早、进展快，轻度肾功能异常即可导致心血管疾病的发生，是慢性肾脏病患者致死、致残的首要原因。慢性肾脏病患者自发病起就可能长期暴露于多种心血管疾病的危险因素中，动脉粥样硬化是心血管疾病的病理基础，而传统危险因素已不能完全解释慢性肾脏病患者心血管疾病的高发病率，部分高龄患者慢性肾脏病的高发病率考虑为动脉粥样硬化和心血管疾病的肾脏损害。故目前认为，慢性肾脏病本身即是心血管疾病的独立危险因素。“,”The incidence and mortality of cardiovascular disease in patients with chronic kidney disease , was significantly higher than that of the general population ,and due to the early onset and fast development , mild renal dysfunction can lead to the occurrence of cardiovascular disease , which is the leading cause of death and disability in patients with chronic kidney disease.Patients with chronic kidney disease may be in long-term exposure to a variety of cardiovascular risk factors since onset of the kidney disease .Atherosclerosis is the pathological basis of cardiovascular disease ,however traditional risk factors cannot entirely explain the high incidence of cardiovascular disease in patients with chronic kidney disease ,high incidence of part of the elderly patients with chronic kidney disease is considered to be the result of atherosclerosis and cardiovascular damage caused by kidney disease.It′s now considered that chronic kidney disease is an independent risk fac-tor for cardiovascular disease .