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目的研究颈动脉粥样硬化斑块与脑梗死及其危险因素的关系。方法应用HP彩色超声仪对153例脑梗死患者的颈动脉进行检测,分为脑梗死侧组和非脑梗死侧组进行颈动脉粥样硬化斑块发生率和狭窄程度的比较,并将患者的病史、个人史和生化检查与颈动脉粥样硬化斑块的关系进行多因素分析。结果脑梗死侧组颈动脉粥样硬化斑块和软斑的发生率较非脑梗死侧组高,两组之间有显著性差异(P<0.05),多元Logistic回归分析显示年龄、低密度脂蛋白、纤维蛋白原和糖基化血红蛋白是影响脑梗死患者颈动脉粥样硬化斑块的独立危险因素。结论颈动脉粥样硬化斑块与脑梗死之间存在着密切关系,多种因素影响颈动脉粥样硬化斑块的形成。
Objective To study the relationship between carotid atherosclerosis plaque and cerebral infarction and its risk factors. Methods The carotid arteries of 153 patients with cerebral infarction were detected by HP color ultrasound system and divided into two groups: side cerebral infarction group and non-cerebral infarction side group. The incidence of carotid artery atherosclerosis and the degree of stenosis were compared. History, personal history and biochemical tests and carotid atherosclerotic plaque relationship between multivariate analysis. Results The incidence of carotid atherosclerotic plaques and soft plaques in the lateral cerebral infarction group was higher than that in the non - cerebral infarction group (P <0.05). Multivariate Logistic regression analysis showed that age, low density lipoprotein Proteins, fibrinogen, and glycosylated hemoglobin are independent risk factors for carotid atherosclerotic plaques in patients with cerebral infarction. Conclusion There is a close relationship between carotid atherosclerosis plaque and cerebral infarction. A variety of factors affect the formation of carotid artery atherosclerotic plaque.