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急性肾前性肾功能衰竭引起的低血容量性休克,已为大家所熟知。肾病合并感染性休克,目前也有报道。本文以原发性肾病综合征(NS)为例,对肾原性休克的发病机理加以探讨,供同道参考。NS患者存在着血液高凝状态和血栓栓塞的危险。大量的实验和临床资料证明,肾炎的发病与免疫有关,而血液凝固异常(肾小球内凝血、血小板的凝集、纤溶迟缓、红细胞的凝集)及低蛋白血症和利尿剂使用等,均可导致微循环障碍和血栓形成,与休克的发生密切相关。
Acute renal failure caused by hypovolemic shock, has been well-known. Renal disease complicated with septic shock, there are also reports. In this paper, nephrotic syndrome (NS) as an example, the pathogenesis of nephrotic shock to be discussed for fellow reference. NS patients have the risk of hypercoagulable state and thromboembolism. A large number of experimental and clinical data show that the incidence of nephritis and immune-related, and abnormal blood coagulation (glomerular coagulation, platelet aggregation, fibrinolysis, erythrocyte aggregation) and hypoproteinemia and diuretic use, etc. Can lead to microcirculation and thrombosis, and the occurrence of shock is closely related.