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目的:探讨肺泡蛋白沉着症(PAP)肺泡灌洗术前后定量CT的应用价值。方法:将我院接诊的15例PAP患者作为研究对象,均进行肺泡灌洗术处理,共计20次,采取定量CT分析PAP肺泡灌洗术前后肺重量、肺总容积、平均肺密度及肺CT值,同时对这些指标进行对比分析。结果:灌洗术后肺总容积有所升高,但与术前比较无统计学意义(P>0.05);其余三个指标术后均有明显下降,与术前相较有统计学意义(P<0.05)。结论:肺泡蛋白沉着症患者肺泡灌洗术前后采取定量CT检查,可以为临床疗效指标提供客观与精确的参考价值,值得借鉴。
Objective: To investigate the value of quantitative CT in alveolar proteinosis (PAP) before and after alveolar lavage. Methods: Fifteen patients with PAP admitted to our hospital were treated with alveolar lavage for 20 times. Quantitative CT was used to analyze the changes of lung weight, total lung volume, average lung density and PAP before and after PAP lavage Lung CT value, at the same time to compare these indicators. Results: After lavage, the total volume of lung increased, but there was no significant difference compared with that before operation (P> 0.05). The remaining three indexes were significantly decreased after operation, which was statistically significant compared with that before operation P <0.05). Conclusions: Quantitative CT examination before and after alveolar lavage in patients with pulmonary alveolar proteinosis can provide objective and accurate reference value for clinical curative effect index, which is worth learning from.