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本文对氯甲烷进行了一系列的毒性实验和车间劳动卫生学调查。结果表明,大鼠吸入490±60mg/m3的氯甲烷6个月出现肝损害,豚鼠吸入5个月出现了震颤症状,随着染毒浓度的增加,上述改变更为明显。劳动卫生学调查表明,当车间空气中氯甲烷年平均浓度为83.53±76.76mg/m3时,工人的神经衰弱症状和肝大的出现率高于对照组。因此,建议我国车间空气中氯甲烷卫生标准为40mg/m3。
In this paper, a series of toxic experiments on chloromethane and the workshop on labor hygiene were conducted. The results showed that the rat suffered from liver damage after 490 ± 60 mg / m3 of methyl chloride inhalation for 6 months and the guinea pig inhalation for 5 months showed tremor symptoms. The above changes were more obvious with the increase of exposure concentration. Labor hygiene survey showed that when the annual average concentration of methyl chloride in the workshop air was 83.53 ± 76.76mg / m3, the incidence of neurasthenia and liver enlargement in workers was higher than that in the control group. Therefore, it is recommended that China’s workshop air chloride standard health 40mg / m3.