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研究旨在比较诊断幽门螺杆菌(Hp)感染7种不同试验的准确性及抑酸治疗对试验结果的影响。 病人和方法:1995年1月至12月因消化不良而行胃镜检测者351例用7种不同试验检测Hp感染,包括:①快速尿素酶法(RUT);②细菌培养法;③直接镜检法;④实验室尿素酶法(LUT);⑤血清抗Hp IgG抗体;⑥血清抗Hp IgA抗体;⑦~(14)C-尿素呼气试验(UBT)。至少3种以上试验阳性者被认为存在Hp感染。所有受试者在入选前均未接受抗Hp治疗。
The aim of the study was to compare the accuracy of seven different tests for the diagnosis of Helicobacter pylori (Hp) infection and the effect of acid suppression on the test results. PATIENTS AND METHODS: 351 patients with endoscopy due to indigestion from January 1995 to December were tested for Hp infection in seven different tests including: rapid urease (RUT); bacterial culture; direct microscopy Method; ④ laboratory urease (LUT); ⑤ serum anti-Hp IgG antibody; ⑥ serum anti-Hp IgA antibody; ⑦ ~ (14) C-urea breath test (UBT). At least three or more positive tests are considered Hp infection. None of the subjects received anti-Hp treatment prior to enrollment.