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同种免疫尽管相对罕见,但仍是造成出生前后发病和死亡的一个原因。目前同种免疫一般发生在下列三组孕妇:①敏感的 Rh阴性母亲,为本世纪60年代后期 Rh 免疫球蛋白应用以前的敏感人群;②在妊娠或分娩后期未及时治疗或即使治疗也出现同种免疫;③母亲被 D 抗原以外的抗原同种免疫。本文目的在于概括自从加强利用超声影像和胎儿监测以后,目前的诊断步骤及一些治疗结果。
Alloimmunization, though relatively rare, is still one of the causes of morbidity and mortality before and after birth. At present allogeneic immunization generally occurs in the following three groups of pregnant women: ① sensitive Rh-negative mother, the late 60s of this century, the application of Rh immunoglobulin sensitive former population; ② in pregnancy or childbirth did not receive timely treatment or treatment even if the same Immune; ③ mothers were antigens other than D antigen immunity. The purpose of this article is to summarize the current diagnostic procedures and some of the treatment outcomes since enhanced use of ultrasound imaging and fetal monitoring.