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目的探析小儿肾病综合征应用低分子肝素治疗的临床效果。方法 60例肾病综合征患儿,按照计算机数表法分为对照组与观察组,各30例。对照组患儿予以常规治疗,观察组患儿予以低分子肝素治疗,对两组患儿临床疗效、尿蛋白、血胆固醇、血清白蛋白含量予以统计比较。结果观察组患儿临床总有效率为96.7%,高于对照组的76.7%,差异具有统计学意义(P<0.05)。治疗前两组患儿尿蛋白、血胆固醇、血清白蛋白含量比较差异无统计学意义(P>0.05)。治疗后观察组患儿尿蛋白、血胆固醇、血清白蛋白含量均优于对照组,差异有统计学意义(P<0.05)。结论小儿肾病综合征应用低分子肝素治疗的临床效果更好,能够显著改善患儿各项临床指标,是一种值得临床广泛应用与普及的治疗方法。
Objective To investigate the clinical effect of low molecular weight heparin in children with nephrotic syndrome. Methods Sixty children with nephrotic syndrome were divided into control group and observation group according to the computer table method, and each group had 30 cases. Children in the control group were treated routinely, and children in the observation group were treated with low molecular weight heparin. The clinical efficacy, urinary protein, blood cholesterol and serum albumin in the two groups were compared statistically. Results The total clinical effective rate in observation group was 96.7%, which was higher than that in control group (76.7%), the difference was statistically significant (P <0.05). Urine protein, blood cholesterol and serum albumin in the two groups before treatment had no significant difference (P> 0.05). After treatment, urinary protein, blood cholesterol and serum albumin in the observation group were better than those in the control group (P <0.05). Conclusion The clinical effect of low molecular weight heparin treatment in children with nephrotic syndrome is better, which can significantly improve the clinical indicators in children. It is a widely used and popular clinical treatment.