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自1885年从植物中分离出匹鲁卡品,并用于治疗青光眼已100多年,但抗青光眼药物研究进展甚少。1977年发现噻玛心安是一个优良的抗青光眼新药,惜尚未能普遍供应。故目前匹鲁卡品仍然是最常用的降眼压药,但它需要进口消耗外汇,而且广大农村也很难得到。长期以来,眼科临床企望能有国产的新降眼压药研制成功和供应临床。我们在从中草药筛选降眼压药过程中,发现石蒜科植物石蒜(Lycoui radata Herb)鳞基的醇提液(以下简称石蒜液)对水负荷兔眼有降
Pilocarpine has been isolated from plants since 1885 and has been used in the treatment of glaucoma for more than 100 years, but little is known about anti-glaucoma drug research. It was found in 1977 that thiazole is an excellent anti-glaucoma drug, but it has not yet been able to supply it universally. Therefore, pilocarpine is still the most commonly used antihypertensive drug, but it needs to import and consume foreign exchange, and the vast rural areas are also hard to get. For a long time, the clinical hope of ophthalmology can have a new home-made intraocular pressure medicine developed successfully and supply clinical. In the process of screening eye drops from Chinese herbal medicine, we found that the alcoholic extract of Lycium radicum (Lycium radicum)