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目的:了解不同类型的慢性前列腺炎精液质量的变化,并评价不同类型前列腺炎对不育症的影响程度。方法:对全部入选的848例慢性前列腺炎患者按照WHO1999年标准进行诊断并按NIH前列腺炎分类方法分为4种亚型,即Ⅱ型、Ⅲa型、Ⅲb型、Ⅳ型,同时采用计算机辅助精子分析(CASA)技术进行精液分析。结果:各组间精液质量参数分析显示:Ⅱ型及Ⅲa型的活精子比例、一级向前运动精子占活精子比例均分别低于Ⅲb型(P<0.01)、Ⅳ型(P<0.01),Ⅱ型及Ⅲa型畸形精子比例则高于Ⅲb型(P<0.01)、Ⅳ型(P<0.01);而Ⅱ型与Ⅲa型、Ⅲb型与Ⅳ型组间则无显著差异。精液中白细胞数Ⅱ型与Ⅲa型(P<0.01)、Ⅲb型(P<0.01)、Ⅳ型(P<0.01)的差异均具有统计学差异,Ⅲa型也与Ⅲb型(P<0.01)、Ⅳ型(P<0.01)有统计学差异,但Ⅲb型与Ⅳ型组间无统计学意义。结论:不同类型慢性前列腺炎对精液质量改变的影响不同,其影响程度的比较为:Ⅱ型、Ⅲa型大于Ⅳ型、Ⅲb型。
Objective: To understand the different types of chronic prostatitis semen quality changes, and evaluate the different types of prostatitis on the impact of infertility. Methods: All the 848 patients with chronic prostatitis were divided into 4 subtypes according to WHO classification of NIH prostatitis according to the standard of 1999, that is, type Ⅱ, type Ⅲ a, type Ⅲ b and type Ⅳ. At the same time, computer-assisted sperm Analysis (CASA) technique for semen analysis. Results: The results of semen quality parameters analysis showed that the proportion of live sperm between type Ⅱ and type Ⅲa and the percentage of sperm in one grade of motile sperm were lower than those of type Ⅲb (P <0.01), type Ⅳ (P0.01) (P <0.01), type IV (P <0.01), but there was no significant difference between type II and IIIa, IIIb and IV. There were significant differences in the number of white blood cell type II and type IIIa (P <0.01), type IIIb (P <0.01), type IV (P <0.01) Ⅳ (P <0.01), but there was no significant difference between Ⅲb and Ⅳ. CONCLUSION: Different types of chronic prostatitis have different effects on semen quality changes, the comparison of the degree of influence is: type Ⅱ, type Ⅲ a is more than type Ⅳ, type Ⅲ b.