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荚膜多糖菌苗免疫保护作用（如对脑膜炎球菌多糖）较差，因它不能刺激Ｔ细胞产生免疫应答，而这种Ｔ细胞介导免疫应答是激活长期的免疫回忆反应所需要的；同时，婴儿对荚膜多糖菌苗免疫反应也较差。在英国，约４０％脑膜炎患者是由奈瑟氏脑膜炎球菌Ｃ群引起；这种细菌对年幼儿
The immunoprotective (ie, against meningococcal polysaccharide) capsular polysaccharide vaccine is poor because it does not stimulate T cells to produce an immune response that is required to activate long-term immune recall responses; at the same time , Infants immune response to capsular polysaccharide vaccine is also poor. In the United Kingdom, about 40% of meningitis patients are caused by Neisseria meningitidis C group;