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目的:探索高原地区脑血管病患者与高尿酸血症的相关性。方法:分析我院2013年—2015年间215例脑血管病病人的临床资料,测得血中尿酸水平,并与门诊正常对照组比较分析。结果:脑出血、蛛网膜下腔出血、脑梗塞和TIA患者的尿酸平均值(mmol/L)分别为431.5±79.36,428.6±81.36,435.2±83.36和430.4±80.36,较正常对照组明显升高。影响脑卒中发生的相关危险因素除年龄、性别、高血压、空腹血糖、低密度脂蛋白等而外,高尿酸血症(hyperuricemia,HUA)也是不容忽视的重要影响因素之一。结论:高原地区脑血管病患者的尿酸水平较正常人高,血尿酸水平>416.5μmol/L是脑卒中的独立危险因素。高尿酸血症可能在高原脑卒中发生方面起着重要的作用。
Objective: To explore the correlation between hyperuricemia and cerebrovascular disease in high altitude area. Methods: The clinical data of 215 patients with cerebrovascular disease in our hospital from 2013 to 2015 were analyzed. The level of uric acid in serum was measured and compared with the normal control group. Results: The mean uric acid (mmol / L) of cerebral hemorrhage, subarachnoid hemorrhage, cerebral infarction and TIA were 431.5 ± 79.36, 428.6 ± 81.36, 435.2 ± 83.36 and 430.4 ± 80.36, respectively, which were significantly higher than those in the normal control group . In addition to age, sex, hypertension, fasting blood glucose, low density lipoprotein, etc., the related risk factors affecting stroke are also one of the important factors that can not be ignored. Conclusion: The prevalence of uric acid in patients with cerebrovascular disease in the plateau is higher than that in normal people. The serum uric acid level> 416.5 μmol / L is an independent risk factor for stroke. Hyperuricemia may play an important role in the development of high altitude stroke.