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目的:探讨脉搏波传导速度与高血压微量蛋白尿的相关性。方法:测定97例高血压住院患者脉搏波传导速度,用放射免疫法检测其尿微量白蛋白,根据检测结果将高血压患者分为微量蛋白尿组和单纯高血压组。比较2组患者脉搏波传导速度,分析其与微量蛋白尿的相关性。结果:2组脉搏波传导速度差异有统计学意义(t=7.41,P=0.000);微量蛋白尿组脉搏波传导速度与尿白蛋白呈线性正相关(r=0.362,P=0.010),单纯高血压组脉搏波传导速度与尿白蛋白无相关关系(r=0.102,P=0.458)。Logistic回归分析,脉搏波传导速度是高血压微量蛋白尿独立预测因子(OR=6.945,95%CI:3.093~15.597)。结论:高血压微量蛋白尿与脉搏波传导速度呈线性正相关,脉搏波传导速度是高血压微量蛋白尿独立预测因子。
Objective: To investigate the correlation between pulse wave velocity and microalbuminuria in hypertension. Methods: The pulse wave velocity of 97 inpatients with hypertension was measured. Urinary microalbumin was detected by radioimmunoassay. Hypertensive patients were divided into microalbuminuria group and simple hypertension group according to the test results. The pulse wave velocity in two groups was compared, and the correlation between them and microalbuminuria was analyzed. Results: There was a significant difference in pulse wave velocity between the two groups (t = 7.41, P = 0.000). There was a linear positive correlation between pulse wave velocity and urinary albumin (r = 0.362, P = 0.010) There was no correlation between pulse wave velocity and urinary albumin in hypertension group (r = 0.102, P = 0.458). Logistic regression analysis showed that pulse wave velocity was an independent predictor of microalbuminuria in hypertension (OR = 6.945, 95% CI: 3.093-15.597). Conclusion: Hypertensive microalbuminuria is positively correlated with pulse wave velocity. Pulse wave velocity is an independent predictor of microalbuminuria in hypertension.