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目的 探讨不同治疗方案对广州地区爆发流行的传染性非典型肺炎的疗效。方法 将 2 0 0 3- 0 2～2 0 0 3- 0 5收治的传染性非典型肺炎按不同治疗方案进行分组 ,比较其治疗效果并进行分析。结果 显示各组抗病毒药物治疗效果差异无显著性 ,但使用糖皮质激素可减少机械通气特别是气管插管的机率。结论 重症患者或出现急性呼吸窘迫综合征者在适当时机使用适当剂量的糖皮质激素及正压无创通气可在一定程度上阻止肺部炎症渗出的进展 ,减少气管插管及降低病死率
Objective To investigate the curative effects of different treatment regimens on the outbreak of SARS in Guangzhou area. Methods Infectious atypical pneumonia was treated by different treatment regimens from 2000 to 2002. The therapeutic effects were compared and analyzed. The results showed that the effect of each group of antiviral drugs was no significant difference, but the use of glucocorticoids can reduce the chance of mechanical ventilation, especially tracheal intubation. Conclusion Severe patients or patients with acute respiratory distress syndrome at the appropriate time using the appropriate dose of glucocorticoid and positive pressure noninvasive ventilation may be to a certain extent, prevent the progression of pulmonary inflammatory exudation, reduce tracheal intubation and reduce mortality