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为评价目前常用的单纯疱疹病毒性脑炎（ＨＳＥ）脑脊液（ＣＳＦ）３项检查方法的临床应用价值，作者按照平行试验的原则，对４３例ＨＳＥ患者同时进行了ＣＳＦ单纯疱疹病毒抗原（ＨＳＶ－Ａｇ）、抗体（ＨＳＶ－Ａｂ）和ＤＮＡ（ＨＳＶ－ＤＮＡ）检测。结果显示：ＨＳＶ－Ａｂ与ＨＳＶ－ＤＮＡ检测的阳性率高于ＨＳＶ－Ａｇ，分别为８６．０％、７６．７％和４８．８％；４３例患者中２项以上阳性者为３６例，占８３．７％。作者认为：对临床疑诊的所谓“散发性脑炎”患者均应同时进行ＣＳＦＨＳＶ３项检测，如２项或３项阳性者可确诊为ＨＳＥ，１项阳性者应高度怀疑为ＨＳＥ，并应早期使用无环鸟苷等有效药物治疗。
In order to evaluate the clinical value of three commonly used tests of HSE cerebrospinal fluid (CSF), 43 patients with HSE were treated with CSFV herpes simplex virus (HSV- Ag), antibodies (HSV-Ab) and DNA (HSV-DNA). The results showed that the positive rates of HSV-Ab and HSV-DNA were 86.0%, 76.7% and 48.8%, respectively. The positive rate of HSV-Ab and HSV-DNA was 36.0% Accounting for 83.7%. The authors believe that the so-called “sporadic encephalitis” in patients with clinical suspicion should be simultaneously CSFSV3 test, such as 2 or 3 were positive for HSE diagnosis, a positive should be highly suspected HSE, and should be early Use acyclovir and other effective drugs.