论文部分内容阅读
目的:探讨干扰素联合更昔洛韦治疗儿童EB病毒感染的效果。方法:收集本院2016年1月至2016年12月收治的63例EB病毒感染患儿,根据治疗方案分为对照组和联合组,其中对照组31例接受重组人干扰素常规治疗,联合组32例接受重组人干扰素联合更昔洛韦治疗,比较两组的治疗有效率及预后相关时间指标(体温恢复正常时间、脾脏缩小时间及住院时间)。结果:两组有效率的差异无统计学意义,但联合组的显效率高于对照组;观察组预后相关时间指标较对照组缩短(P<0.05)。结论:干扰素联合更昔洛韦治疗儿童EB病毒感染的效果较好,缩短患者预后改善时间,具有较好的临床应用价值。
Objective: To investigate the effect of interferon plus ganciclovir in the treatment of children with Epstein-Barr virus infection. Methods: Sixty-three children with Epstein-Barr virus (EBV) infection were collected from January 2016 to December 2016 in our hospital. According to the treatment regimen, they were divided into control group and combination group. Among them, 31 patients in control group received routine IFN treatment, Thirty-two patients received recombinant interferon plus ganciclovir. The therapeutic efficacy and prognosis-related time indexes (body temperature recovery time, spleen shrinkage time and hospital stay time) were compared between the two groups. Results: There was no significant difference between the two groups in efficiency, but the effective rate of the combination group was higher than that of the control group. The prognosis related time of the observation group was shorter than that of the control group (P <0.05). Conclusion: Interferon combined with ganciclovir is effective in treating children with Epstein-Barr virus infection and shortening the prognosis and prognosis of children with good clinical value.