论文部分内容阅读
目的:对不同年龄儿童急性下呼吸道感染的病原菌分布特点进行探究,了解其分布情况和耐药性。方法:以2014年9月至2016年9月我院急性下呼吸道感染儿童中痰液分离出的所有菌株679株进行回顾性分析,并探究这些常见病原菌的分布情况、分布特点以及儿童年龄段分析,并按照美国国家临床实验室标准委员会的标准展开。结果:本次研究结果显示,在患儿的感染病原菌感染方面,占比最大的病原菌构成主要集中在肺炎链球菌、大肠埃希菌、金黄色葡萄球菌和肺炎克雷伯菌四种,另外还包括真菌、阴性葡萄球菌、不动杆菌和其它。对2014年-2015年及2015年-2016年两个时间段的分布情况来看,肺炎链球菌、大肠埃希菌、金黄色葡萄球菌、肺炎克雷伯菌四项仍然是比例最大的部分。其中金黄色葡萄球菌出现了明显下降,但肺炎克雷伯菌出现了提升。而其它几项的结果对比相对平稳。在感染儿童年龄分布情况上来看,综合整体的分布,患儿感染疾病的年龄集中于1个月以内以及1个月-1岁两个阶段。这两个阶段的患儿身体体质虚弱,抵抗力较差,因此患病几率高。三项列表中的数据差异对比都非常显著,具有统计学意义(P<0.05)。结论:分离结果来看,儿童急性下呼吸道感染由多种菌株构成,但是在年龄分布上具有显著的差异性,因此在后续的治疗和研究过程中需要注意到这方面的问题,并将其作为重要的参考依据。
Objective: To investigate the distribution of pathogenic bacteria in acute lower respiratory tract infection in children of different ages to understand their distribution and drug resistance. Methods: A total of 679 isolates from sputum from children with acute lower respiratory tract infection in our hospital from September 2014 to September 2016 were analyzed retrospectively, and the distribution, distribution characteristics and age analysis of these common pathogens , And in accordance with the standards of the National Clinical Laboratory Standards. Results: The results of this study showed that in the children infected with the pathogen infection, the largest proportion of pathogenic bacteria mainly concentrated in Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae four other Including fungi, negative staphylococci, Acinetobacter and others. For the distribution of the two periods from 2014 to 2015 and from 2015 to 2016, four strains of Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae are still the largest proportion. Staphylococcus aureus appeared in which a significant decline, but Klebsiella pneumoniae increased. The contrast of several other results is relatively stable. In terms of the age distribution of infected children, the overall overall distribution of children’s illness is concentrated in less than one month and in two stages of one month and one year. Children in these two stages of physical weakness, poor resistance, so high risk of illness. The differences of the data in the three lists were all significant and statistically significant (P <0.05). Conclusion: According to the separation results, children with acute lower respiratory tract infection consist of many strains, but have significant differences in age distribution. Therefore, it is necessary to pay attention to this problem in the follow-up treatment and research, Important reference.